Cornerstone Infusion Management Solutions
Turnkey In-Office Infusion Therapy
Cornerstone empowers physicians to provide personalized, connected care for high-risk patients through our comprehensive in-office infusion management solutions. By moving infusion services from hospitals to the provider’s office, we help practices optimize “site of care” strategies—reducing healthcare costs while enhancing clinical oversight.
Integrating infusion therapy directly into your practice eliminates care fragmentation. Instead of referring patients to external facilities, providers gain seamless visibility into treatment compliance and medication response. This continuity ensures that the prescribing physician and the infusion team remain in constant alignment, leading to safer, more timely interventions.
Advantages of In-Office Infusion Therapy
Offering in-office infusion therapy not only improves continuity of care, convenience, accessibility, and adherence—all critical components for successful outcomes—it also provides significant benefits for physicians and patients alike.


Provider Benefits
Transitioning infusion services in-office offers a distinct advantage in today’s value-based care landscape. By retaining patients within the practice ecosystem, physicians significantly reduce total care costs compared to Hospital Outpatient Departments (HOPDs) while capturing valuable ancillary revenue streams.
This model positions the practice as a comprehensive “Center of Excellence,” strengthening its reputation for holistic disease management. Ultimately, offering an all-in-one service location drives practice valuation, attracts new patient volume, and ensures long-term financial sustainability.
Patient Benefits
For patients managing chronic conditions, the environment of care is critical to therapeutic adherence. In-office infusions provide a familiar, low-anxiety setting that encourages appointment compliance, distinct from the stress of high-volume hospital centers. This lower-volume approach is clinically superior for immunocompromised patients, significantly reducing the risk of exposure to nosocomial infections.
Beyond clinical safety, Cornerstone removes barriers to care by handling financial counseling and prior authorizations, ensuring patients can access necessary biologics without administrative hurdles.

Getting started at TwelveStone Health is easy
Cornerstone’s turnkey solution is designed to help physician practices get up and running with minimal disruption to operations.
No capital investment required
Streamlined implementation
Leverages existing space
Cornerstone licensed clinicians provided
Site development and interior design support
Includes infusion chairs and other standard furniture & equipment
Lease-share opportunity
Direct feedback on patients shared in EMR
As our nation ages, new novel therapies come to market, and the incidence of chronic disease increases, the need for infusion services will grow exponentially. There’s never been a better time to implement in-office infusion services, and Cornerstone can help make it happen.
FREQUENTLY ASKED QUESTIONS
How much does infusion therapy cost?
The cost varies significantly depending on the specific medication, dosage, treatment frequency, and your insurance plan (commercial or government). Expenses generally encompass the drug itself, medical supplies, and nursing administration. We recommend contacting your insurance provider directly to understand your specific copays, deductibles, and out-of-pocket maximums.
What should I wear to an infusion appointment?
We recommend wearing loose-fitting, comfortable clothing. Because body temperature can fluctuate during treatment, dressing in layers is helpful. Please ensure your sleeves can be easily rolled up to allow the nurse clear access to your arm or port site. If you have a chest port, a V-neck or button-down shirt is ideal to provide access without disrobing.










