Pediatric Infusion Therapy in the Southeast
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Children with complex medical needs sometimes require IV medications that oral treatments cannot effectively deliver. TwelveStone Health Partners provides clinically monitored pediatric infusion therapy across more than 30 outpatient centers throughout Tennessee, Kentucky, Georgia, Mississippi, and Virginia, helping families access specialized care closer to home.
Every visit takes place in a private infusion suite designed for comfort, with recliners, Wi-Fi, and refreshments available during treatment. Our experienced infusion nurses closely monitor your child throughout the entire appointment to support both safety and comfort.
Why Patients Choose TwelveStone for Infusion Therapy
35+ Year Clinical History
In community pharmacy and professional infusion therapy treatments
30+ Regional Infusion Centers
Across Tennessee, Kentucky, Georgia, Mississippi, and Virginia
Clinical Oversight
From PharmD-led teams with continuous registered nurse monitoring
Administrative Support
For insurance benefits verification and prior authorization management
Home Infusion Options
For eligible patients requiring nursing support at their residence
Understanding Pediatric Infusion Therapy
Infusion therapy delivers medications directly into the bloodstream through an IV or other approved access device. Pediatric infusions may be recommended when oral medications are no longer effective, are difficult to tolerate, or cannot adequately manage a child’s condition. Every treatment plan is coordinated closely with your child’s prescribing specialist to ensure safe and appropriate care.
Our clinical team supports children receiving infusion therapies for conditions such as:
- Autoimmune and inflammatory conditions, including Crohn’s disease and juvenile arthritis
- Neuromuscular and neurologic disorders that require biologic therapies
- Immune support therapies, including immunoglobulin replacement and primary immunodeficiency treatment
- Serious infections requiring intravenous antibiotic therapy
TwelveStone administers more than 62 medications across our regional infusion center locations to help families manage complex chronic conditions closer to home. All medications are prescribed based on your child’s diagnosis, treatment plan, and physician recommendations.

What to Expect During Your Child’s Infusion Visit
Knowing what to expect can help children and caregivers feel more comfortable before treatment day. At TwelveStone, pediatric infusion appointments follow a clear step-by-step process designed to support safety, comfort, and communication throughout the visit.
Before the Visit
Our clinical team reviews all pre-infusion instructions before your appointment. We may recommend increasing water intake the day before treatment to support hydration and simplify vein access. Families are encouraged to bring a favorite comfort item and dress children in loose, comfortable clothing.
During the Treatment
After reviewing vitals, medications, and allergies, nurses prepare the IV access site. Depending on your child’s care plan, treatment may be administered through a peripheral IV, PICC line, central line, or implanted port.
Medications are delivered through specialized infusion pumps while nurses continuously monitor your child throughout the session.
After the Session
Once treatment is complete, nurses remove the IV or secure the access line before a brief observation period. Families receive home care instructions before discharge, and our patient resources page includes additional information to help you prepare for future visits.
TwelveStone Pediatric Infusion Centers
Locations in TN, KY, GA & VA
Clinical Safety and Monitoring Standards
Safe pediatric infusion therapy depends on consistent monitoring, clear clinical protocols, and experienced nursing oversight. Our care teams follow established outpatient infusion safety procedures throughout every stage of treatment.
Our outpatient infusion safety process includes:
- Screening for recent illnesses, allergies, and medication changes before treatment
- Baseline vitals and ongoing nurse monitoring during infusions
- Controlled medication administration using specialized infusion pumps
Because every medication carries different risks and monitoring requirements, our nursing team coordinates closely with your child’s prescribing specialist throughout treatment.
Each care plan also includes PharmD-led oversight. Pharmacists review pediatric dosing, evaluate medication compatibility, and support sterile medication preparation within our specialty pharmacy workflow.
Navigating Insurance and Cost for Pediatric Infusions
Many pediatric infusion medications require insurance approval and benefits verification before treatment begins. Our intake specialists manage this process directly with families, providers, and insurance carriers to help reduce delays in care.
Our Authorization Process
Our team verifies commercial insurance, TennCare, and other eligible provider benefits before treatment begins. We coordinate directly with your child’s physician to collect clinical documentation, submit prior authorizations, and track approvals.
Before scheduling treatment, we explain expected out-of-pocket costs and answer questions about insurance coverage or financial responsibilities.
Financial Assistance and Home Care
When available, we help families explore manufacturer copay programs and nonprofit financial assistance resources. In some cases, home infusion may also be evaluated as a clinically appropriate treatment option for your child.

Ready to Schedule Pediatric Infusion Therapy?
TwelveStone Health Partners helps families access safe, clinically monitored pediatric infusion therapy throughout the Southeast. From insurance coordination to treatment-day support, our team guides families through every stage of care with a focus on comfort, communication, and safety.
Explore our patient resources to prepare for your child’s first appointment, or contact our team to begin the intake process.
Less Stressful Infusion Treatment
Easy
Our streamlined scheduling process makes it easy for you to plan.
Our Focus Is On You
You are our priority, and our custom treatment options mean that you get care tailored to your needs.
Expertise
Our expert clinical staff has experience in a wide range of conditions. You’ll always have an expert at your side when you need them.
We meet all of your needs for pediatric infusion treatment on your schedule.

WHAT TO EXPECT
We create a custom treatment plan. You relax in a spacious suite with snacks and Wi-Fi!
Our certified techs work with other members of your care team to ensure you’ve got just what you need.
We’ll deal with the insurance company and work to make sure you pay as little as possible out of pocket.