Chronic and complex conditions often require medications that cannot be effectively delivered through oral treatments alone. TwelveStone Health Partners provides advanced care solutions designed to support patients managing long-term and specialty conditions across Tennessee, Kentucky, Georgia, Mississippi, and Virginia.
Patients can access care through:
- Private suite infusion centers in 30+ locations
- Personalized home-based infusion care for eligible patients
Our clinical team coordinates directly with your referring physician and manages insurance requirements to streamline your care from start to finish. Each visit is designed to prioritize safety, comfort, and clinical outcomes in a professional setting.
Why Patients Choose TwelveStone for Infusion Therapy
35+ Year Clinical History
In community pharmacy and professional infusion therapy treatments
30+ Regional Infusion Centers
Across Tennessee, Kentucky, Georgia, Mississippi, and Virginia
Clinical Oversight
From PharmD-led teams with continuous registered nurse monitoring
Administrative Support
For insurance benefits verification and prior authorization management
Home Infusion Options
For eligible patients requiring nursing support at their residence

How Infusion Therapy Improves Treatment Outcomes
Infusion therapy delivers medication directly through an IV or injection under professional supervision. This approach bypasses the digestive system, allowing for faster absorption and more consistent dosing. It is commonly used to manage complex or chronic conditions that require precise administration.
Why Specialists Prescribe Infusion Therapy
Physicians often recommend infusion therapy for medications that require precise dosing, controlled administration, or ongoing monitoring. Common use cases include:
- Biologic therapies for autoimmune conditions
- Immune globulin (IVIG) treatments
- Specialty antibiotics
- Osteoporosis therapies
Clinical administration allows for real-time monitoring of patient response and safety. At TwelveStone, PharmD-led teams and registered nurses oversee every session to ensure strict adherence to clinical protocols. We administer 62 specialty medications, including biologics such as Remicade, Entyvio, and Ocrevus, in private suites designed for comfort.
Your physician directs all prescribing decisions, while TwelveStone acts as your clinical partner to coordinate medication delivery and monitoring. Our team works directly with your doctor to guide you from prescription to your first appointment at one of our regional centers.
Choosing a Site of Care: Infusion Center vs. Home Infusion
Choosing the right location for infusion therapy depends on balancing clinical safety and personal convenience. Patients typically receive care in hospital outpatient departments, independent infusion centers, or at home.
Hospital settings provide intensive monitoring for high-risk medications, while independent infusion centers offer private suites and flexible scheduling.
Several factors determine the most appropriate setting:
- The medication’s risk profile and required monitoring levels
- Patient mobility and proximity to a clinical facility
- Payer requirements and potential out-of-pocket cost differences
- Prescribed frequency and the length of each session
TwelveStone facilitates care through our infusion center services and home infusion programs. Our clinical coordinators work with physicians and insurance providers to verify which setting meets clinical and payer guidelines. To confirm eligibility for a specific location, request a consultation with our intake team.
Infusion Therapy Medications and Conditions We Treat
TwelveStone Health Partners administers 62 unique infusion therapy treatments across several clinical specialties.
Your prescribing physician determines the exact medication and dosage for your care plan, while our clinical team handles safe administration. We maintain an extensive inventory to support patients managing chronic autoimmune, inflammatory, and infectious conditions throughout the Southeast.
Our clinical specialties include:
- Neurology & MS: Ocrevus, Tysabri, Briumvi, and Lemtrada
- Gastroenterology & Rheumatology: Entyvio, Stelara, Omvoh, Remicade, and biosimilars like Avsola or Renflexis
- Dermatology & Immunology: Skyrizi, Saphnelo, and IVIG (Immune Globulin)
- Osteoporosis & Endocrinology: Evenity and Tepezza
- Pulmonology & Infectious Disease: Xolair, Nucala, Fasenra, Tezspire, and acute care antibiotics
Browse our full list of infusion therapy medications below:
Medication availability varies by location and insurance requirements. To confirm your medication is in stock and begin the scheduling process, contact TwelveStone or use our online referral portal.
Our clinical coordinators verify benefits and manage communication with your doctor to support a smooth transition to our care. Once your therapy is scheduled, our team prepares everything for a comfortable and efficient visit.
Insurance Coverage and Support for Infusion Therapy
Biologic medications are advanced treatments derived from living organisms. Because of their complexity, insurance providers may require the use of biosimilars, which are highly similar alternatives with no meaningful clinical differences in safety or effectiveness.
Obtaining insurance approval for infusion therapy treatments involves several standard administrative steps:
- Benefits verification to confirm plan coverage and patient responsibility
- Prior authorization to establish medical necessity with insurance providers
- Step therapy protocols requiring specific preferred medications first
- Enrollment in manufacturer copay assistance programs for eligible patients
TwelveStone employs financial counselors and care coordinators to manage these requirements.
Our team handles the paperwork and communicates with insurance providers to keep your clinical schedule on track. If you have questions about your plan, contact TwelveStone to speak with a coordinator.
What to Expect During Your Infusion Visit
A typical visit follows a consistent clinical flow designed for safety and patient comfort. Our nursing staff manages every step of the medical protocol to give you a predictable, low-stress experience.
- Check-in and vitals assessment
- Review of prescriber-ordered pre-medications such as antihistamines
- IV placement and medication pump connection
- Continuous clinical monitoring during and after administration
- Observation period and detailed discharge instructions
We provide infusion center services in private suites rather than open clinical bays. Each room features reclining chairs, WiFi, refreshments, and blankets to help you relax. Most suites include dedicated seating for a caregiver.
To prepare, wear loose sleeves and arrive well-hydrated to assist with IV access. For patients who welcome spiritual support, a company chaplain and prayer are available. Contact TwelveStone to speak with our intake team about your first appointment or to manage your ongoing treatment schedule.
Common Questions About Infusion Therapy Treatments
If you are ready to transition, contact TwelveStone or request a consultation through our online intake portal.










