Multiple Sclerosis Disease Infusion Treatment
Living with multiple sclerosis means relying on a care team that understands the challenges of long-term treatment. TwelveStone Health Partners provides infusion therapy services for patients with relapsing and progressive forms of MS who have been prescribed disease-modifying therapies by their neurologist.
Our clinical coordinators help manage prior authorizations and insurance requirements, while our nursing teams deliver attentive care in a comfortable outpatient setting across Tennessee, Kentucky, Georgia, Mississippi, and Virginia.
Multiple Sclerosis Medications
Clinical Care Partners
Patients and referring neurologists choose TwelveStone because we combine clinical oversight, insurance support, and convenient access to infusion services throughout the Southeast.
Multiple Sclerosis Infusion Medications We Administer
Many disease-modifying therapies for multiple sclerosis are administered through IV infusion and require clinical monitoring during treatment. TwelveStone works closely with your prescribing neurologist to follow the treatment plan, dosing schedule, and monitoring requirements specific to your therapy.
Our clinical team manages every stage of the infusion process, from medication preparation and administration to patient monitoring and post-treatment documentation. After each visit, clinical reports are shared with your physician to support coordinated care.
We administer a variety of infusion therapies used in multiple sclerosis treatment, which may include:
- Ocrevus (ocrelizumab), an anti-CD20 therapy given twice yearly
- Tysabri (natalizumab), administered every four weeks
- Other specialized options such as Lemtrada or Briumvi
Medication availability varies by physician orders, clinical appropriateness, and individual clinic capabilities. To learn more about our infusion services or verify treatment availability, contact our team or explore our infusion center services.
Understanding MS Infusion Schedules
Infusion appointments may last anywhere from two to six hours depending on the medication prescribed, infusion protocol, and observation requirements. Treatment schedules vary by therapy, making it important to understand what to expect before your visit.
Typical Ocrevus Scheduling
This B-cell-targeting therapy typically begins with two starter infusions administered two weeks apart, followed by maintenance doses every six months. Confirm this specific regimen with your neurologist before starting.
Alternative Anti-CD20 Protocols
Other IV biologics may use different visit cadences or shorter maintenance protocols depending on the medication, patient tolerability, and site guidelines.
Regardless of the medication, clinical safety protocols remain constant. Every session includes pre-infusion screening for infection risks, active observation for potential reactions, and strict adherence to your prescriber’s monitoring plan.
Need help understanding your treatment schedule? Our care coordinators can explain what to expect and help you find a convenient infusion location.
Tysabri Safety Protocols: JCV Monitoring and Care Coordination
Patients receiving Tysabri® often have questions about JCV testing and ongoing safety monitoring. Your neurologist determines the appropriate testing schedule and evaluates results as part of your overall treatment plan.
Treatment decisions remain under the direction of your neurologist, who considers your medical history, imaging results, and therapy response when recommending ongoing care.
TwelveStone supports these treatment plans by providing scheduled infusions, clinical monitoring, and communication with your prescribing physician throughout your care journey.
How to Start Your MS Infusion Treatment
Beginning infusion therapy can feel overwhelming, but our care coordinators guide patients through each step of the process—from referral and insurance verification to scheduling and ongoing support.
- Referral & Intake: After your neurologist sends the referral, we manage the medical records transfer. Start this intake process through our patient resources page.
- Verify Coverage: Our financial counselors verify your benefits, manage prior authorizations, and identify available copay assistance programs to reduce your out-of-pocket costs.
- Schedule Your Visit: We coordinate appointments around your schedule across our 30+ Southeast clinics. Use our infusion centers map to find a convenient location.
- Infusion Day: Relax in a private suite with a comfortable recliner, Wi-Fi, TV, refreshments, and warm blankets. Nurses handle check-in, vitals, premeds, IV placement, and continuous safety monitoring.
- Aftercare: We schedule your next appointment, send clinical reports to your neurologist, and discuss which symptoms or medication changes to report between visits.
Your MS Treatment, Fully Supported
Managing multiple sclerosis treatment involves more than receiving medication. TwelveStone coordinates scheduling, insurance verification, and communication with your care team so you can focus on your health and daily life. If your neurologist has prescribed infusion therapy, our team is ready to help you get started.
Ashley Mcgee
Absolutely loved this place amazing staff and made you feel well taken care of! Would give more than 5 if I could on the stars! 🩷⭐️⭐️⭐️⭐️
David Brandes
Ronetta Witherspoon
Mandy Leitsch
Kay Duncan
Hardly no waiting, awesome nurses. A good place to have to go get infusions.
Robert Holloway
Minnie Toler
They were so welcoming and caring.They had a whiteboard with a greeting and personal welcome from their staff. They also always made sure that I was always comfortable.
Maurice Carter
I've been twice so far for my monthly injection. These are the kindest, nicest, most pleasant people! But also quick and efficient. I was in and out in less than 10 minutes this week.
Ashley Mondesir
I had an absolutely incredible experience at Twelvestone in Smyrna. Loraine, Leah, and Leoneed were fantastic. All so caring, patient, and attentive. I have had a longtime fear of needles but knowing I will have the support of such a lovely team with those incredible women when I come in for infusions will put me at such ease. Fantastic team!
Marion Jones
Domitila Craighead
I have been using Twelve Stone for almost three years now. The staff is very caring and always trying to make the experience as pleasant as possible. They are always willing to answer any questions you may have and do everything to make you comfortable
Tiffany Smith
catherine jameson
Nice comfortable atmosphere. The staff was very proficient, knowledgeable and friendly and made me feel very comfortable In spite of my nervousness and apprehension of getting the infusion. Thanks for your professionalism.
Catherine Jameson
KentuckyGuy
Very professional and kind staff. Sadly, I’ve had to use them twice now. If you end up at TwelveStone know that you are in good hands.
A Williams
We had a very pleasant and relaxing experience at TwelveStone Infusion center today for my mom’s treatment! Everyone in the office was extremely nice and welcoming. We really felt at home there and the snacks were a huge blessing! Thank you Jessica, Sarah and Megan, y’all are amazing!! And Jennifer at the front, we appreciate your kindness and helpful heart!
Terri Gamble
Great experience at Twelvestone Infusion center. Great location. The facility was clean, individual rooms made me comfortable while getting my infusion. The. . receptionist to nurses were friendly and efficient. Highly recommend using them.
Vk Reece
Sarah and Stacy were jewels. It started at the Reception desk and in the infusion room. Everything went Exceptionally well. THANK YOU ❣️
Sky Stephens
I would recommend this facility to everyone. Ms Chelsea and Ms Jordan were so helpful. These ladies are amazing... Thank you for taking care of my dad.... 100% And 5 Stars for me
Rachel McClure
Even though I go there for treatment, I always enjoy going. That bunch there is like family. I’ve never been to any other place that makes each patient feel so special. Highly recommend Twelve Stone in Murfreesboro Tn.
Charmayne Calhoun
They always have the best nurses and practitioners there. The front office lady is really nice. I like how they run a "tight schedule" in the most respectful way. Making sure all scheduled patients are seen on time. Great facility to get your infusions from.
Charmaine Williams
Rachel Lee
This is a wonderful place to get your infusions done. The staff are very friendly and welcoming and very knowledgeable with their nursing care. The facility is very home-like and comforting. Their God centered environment practice was refreshing to see. I 10/10 recommend.
Sue Hirsbrunner
Everyone was so kind and helpful. My nurses were Meagan and Stephanie. They were both very helpful. It was very interesting and I really liked the facility and especially my nurse Stephanie.
Norma Velasco
Everyone at this facility very pleasant and informative. So glad my Physican referred me to this location. See
Leigh Tribble
While one would hope that you would never have to go to a facility of this nature, I can say with complete honesty that we felt nothing but empathy, kindness and heartfelt care at this infusion center. Absolutely the most professional and kind medical facility and staff we have encountered.
Organizational Resources
The Multiple Sclerosis Foundation is a non-profit organization that is passionate about supporting people living with MS and guiding them down the path to a happy, healthy and self-sufficient life.
The Myasthenia Gravis Association (MGA) is dedicated to supporting individuals, families, friends, and communities impacted by increasing public awareness, providing educational opportunities, and fostering meaningful connections with one another.
Conquer Myasthenia Gravis provides patient support and education, raises MG awareness, provides education for healthcare professionals, and raises funds for vital medical research.
New Patient Resources
Healthcare Costs
- Patient Assistance Programs
- Cost drivers of Multiple Sclerosis
- Health Care Cost Assistance Guide
Multiple Sclerosis Infusion Therapy FAQs
