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Chronic Conditions

Myasthenia Gravis

Living with Myasthenia Gravis is a challenge. Let TwelveStone make life easier with a care team built around you.
 
Comprehensive support to help you manage your condition – physically, financially, and spiritually. Learn More

Myasthenia Gravis Medications

  • Imaavy
  • Immune Globulin
  • Rystiggo
  • Soliris
  • Ultomiris
  • Vyvgart
  • Vyvgart Hytrulo

Living with myasthenia gravis means managing fluctuating muscle weakness and fatigue that can interfere with everyday life. When your neurologist prescribes infusion therapy, TwelveStone Health Partners provides neurologist-directed infusion treatments tailored to your individualized care plan to help support symptom management.

Our experienced clinical team coordinates insurance prior authorizations, benefits verification, scheduling, and ongoing care navigation to simplify your treatment experience. With more than 30 locations across the Southeast, we provide comfortable, compassionate infusion care in private outpatient suites designed around your needs.

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Person holding the lower leg and ankle, illustrating leg muscle weakness that may occur among the signs and symptoms of myasthenia gravis.

Evaluating Myasthenia Gravis Symptoms and Urgency

Fluctuating muscle weakness that worsens with activity and improves with rest is one of the hallmark symptoms of myasthenia gravis. Recognizing these changing symptoms can help you understand when to contact your healthcare provider and when immediate medical attention may be necessary.

Identifying Common Symptom Patterns

Early symptoms of myasthenia gravis often affect the eyes, causing drooping eyelids (ptosis) or double vision. As the condition progresses, bulbar symptoms may develop, leading to difficulty chewing, swallowing, or speaking, along with muscle weakness in the neck, arms, or legs.

A myasthenic crisis is a medical emergency. Call 911 immediately if you experience severe difficulty breathing, are unable to swallow saliva, or notice a sudden, significant loss of muscle strength.

If your symptoms remain difficult to manage despite your current treatment plan, talk with your neurologist about whether infusion therapies such as IVIG or targeted biologics may be appropriate. Once prescribed, TwelveStone Health Partners can coordinate benefits verification, prior authorizations, financial assistance resources, and scheduling at a convenient location near you.

Comparing IVIG and Biologic Therapies for Myasthenia Gravis

IVIG and biologic therapies both help manage myasthenia gravis, but they work in different ways. Intravenous immunoglobulin (IVIG) provides broad immune support, while biologic therapies target specific immune pathways. Your neurologist will recommend the most appropriate option based on your symptoms, antibody status, and overall treatment goals.

IVIG is often used to manage symptom flare-ups, provide short-term support during treatment changes, or serve as maintenance therapy for some patients. It delivers healthy donor antibodies through an intravenous infusion to help regulate immune activity. Because side effects such as headaches may be affected by infusion rates and hydration, your clinical team closely monitors each treatment session.

Patient receiving IVIG therapy in a clinical setting as part of treatment for myasthenia gravis.

Biologic therapies target more specific parts of the immune system. FcRn inhibitors, such as Vyvgart, help lower harmful IgG antibody levels. Complement inhibitor therapies reduce immune system activity that contributes to damage at the neuromuscular junction in certain subtypes of myasthenia gravis.

Biologic therapies require ongoing clinical monitoring, and your care team may delay treatment if you develop an active infection or another condition that could affect your safety.

Once your neurologist prescribes your therapy, TwelveStone Health Partners coordinates benefits verification, prior authorizations, medication access, and scheduling to help streamline the treatment process. Contact our team to establish care and schedule your infusions.

What to Expect During Your Myasthenia Gravis Infusion

Before your appointment, our clinical intake team works directly with your prescribing neurologist to verify treatment orders, complete benefits verification, and obtain any required insurance prior authorizations. This coordination helps resolve coverage details before your visit so you can focus on your care.

Modern infusion clinic hallway and reception area at TwelveStone Health Partners facility
  • Check in and confirm your appointment with the front desk staff.
  • Have your vital signs taken and your IV placed by a registered nurse.
  • Receive any prescribed pre-medications before your infusion begins.
  • Complete your infusion while your clinical team monitors your comfort and response.
  • Remain for a brief observation period if your treatment requires it.

Preparing ahead of time can help make your infusion visit more comfortable. Drink plenty of fluids for two days before and after your appointment, as staying hydrated may help reduce the risk of post-infusion headaches.

We also recommend wearing comfortable layered clothing, bringing a book or other entertainment, and packing soft, easy-to-chew snacks if muscle fatigue affects eating. If your treatment includes sedating pre-medications, arrange for someone to drive you home afterward.

Choosing the Right Site of Care for Myasthenia Gravis Infusions

Understanding Insurance Coverage and Financial Assistance

Where you receive your infusion therapy can affect both your treatment experience and overall convenience. Hospital outpatient departments may involve longer wait times and more complex scheduling, while home infusion may be appropriate for certain patients with limited mobility or specific clinical needs. Independent outpatient infusion centers offer expert clinical supervision in a comfortable setting while allowing many patients to receive treatment closer to home.

With more than 30 locations across Tennessee, Kentucky, Georgia, Mississippi, and Virginia, TwelveStone Health Partners makes advanced outpatient infusion care more accessible throughout the Southeast. 

Patients receive individualized care in private infusion suites, while our team manages prior authorizations, benefits verification, and scheduling. We also help eligible patients explore copay assistance and foundation support programs based on their insurance coverage.

In addition to therapies for myasthenia gravis, TwelveStone Health Partners administers infusion treatments for other neurologic conditions, including medications such as Uplizna when prescribed by a specialist. If you’re exploring your treatment options, our care coordinators can help explain insurance coverage, financial assistance resources, and the next steps for beginning therapy.

Organizational Resources

 Myasthenia Gravis Foundation of America, Inc. (MGFA) is the leading health-based non-profit solely committed to finding a cure and better treatments for people living with the neuromuscular disease Myasthenia Gravis.

Learn more

The National Multiple Sclerosis Society is working toward an MS-free-funding research, spreading symptoms and treatment awareness, publishing news stories and connecting patients to caregivers.

Learn more

The Multiple Sclerosis Foundation of America (MSAA) provides online information about MS diagnoses and treatment plans, as well as connections to various caregivers and helplines.

Learn more

New Patient Resources

Frequently Asked Questions About Myasthenia Gravis Infusion

Infusion therapy begins with a prescription from your neurologist. Once your treatment is ordered, our clinical intake team coordinates with your physician’s office to collect the necessary medical records, verify treatment orders, and begin the insurance approval process. You can get started by submitting a request through our online contact form to connect with a dedicated care coordinator.

An IVIG infusion typically lasts between three and six hours, depending on your prescribed dose and how well you tolerate the treatment. During your first few infusions, your care team may administer the medication more slowly to monitor your response and help minimize side effects. Future appointments may follow a similar schedule or be adjusted based on your individual treatment plan.

Staying well hydrated for forty-eight hours before and after your infusion may help reduce the likelihood of post-infusion headaches. Your care team may also recommend pre-medications, such as acetaminophen or anti-inflammatory medications, based on your individual needs. If you experience a severe or persistent headache accompanied by symptoms such as fever or a stiff neck after your infusion, contact your healthcare provider immediately.

IVIG provides broad immune support by delivering healthy donor antibodies, while biologic therapies target specific proteins or immune pathways involved in myasthenia gravis. Your neurologist will recommend the most appropriate option based on your antibody status, disease subtype, symptoms, and medical history. Although both therapies help manage the condition, they work through different mechanisms.

Many commercial insurance plans and Medicare cover infusion therapies for myasthenia gravis when they are medically necessary. Before your first appointment, our team verifies your benefits, completes any required prior authorizations, and explains your expected coverage. We also help eligible patients identify copay assistance and foundation support programs that may reduce out-of-pocket costs.

Not necessarily. Many patients receive routine myasthenia gravis infusions in a comfortable outpatient infusion center rather than a hospital. In some situations, home infusion may also be an option, depending on your prescribed therapy, overall health, and the level of monitoring recommended by your neurologist. Your healthcare team will determine the most appropriate site of care for your treatment.

Ready to begin infusion therapy in a comfortable, supportive outpatient setting? Explore our infusion center locations to find the TwelveStone Health Partners clinic nearest you, or contact our care team to learn more about the next steps for starting treatment.