Medically monitored infusion care in a spa-like setting.
- Convenient Location
- Relaxing, Private Suites
- Wi-Fi, Snacks & Drinks
Speak to Our Team
"*" indicates required fields



Less Stressful Infusion Treatment
Easy.
Our streamlined scheduling process makes it easy for you to plan.
Our Focus Is On You.
You are our priority, and our custom treatment options mean that you get care tailored to your needs.
Expertise.
Our expert clinical staff has experience in a wide range of conditions. You’ll always have an expert at your side when you need them.
We Love Our Patients
KNOXVILLE, TN Infusion Center
We can help you manage your condition so you experience fewer hospital stays and more time at home where you belong.
- 8880 Cedar Springs Ln
Suite 103
Knoxville, TN 37923 - 7am – 5pm | Monday – Friday
- 844-893-0012
Facility Gallery








WHAT TO EXPECT
We create a custom treatment plan. You relax in a spacious suite with snacks and Wi-Fi!
Our certified techs work with other members of your care team to ensure you’ve got just what you need.
We’ll deal with the insurance company and work to make sure you pay as little as possible out of pocket.
Here’s what our patients have to say.
Twelve Stone is fantastic! The staff is professional, personable and makes you feel like family. Our first experience could not have been better. Open communication and a feeling of comfort and relaxation from the moment we arrived. Everyone was so helpful and you could tell they enjoyed their job and loved their team. We feel so blessed to be at Twelve Stone for our transfusion treatments. The snacks and hot chocolate are the perfect touch!
Scott Batey
in the last week via Google
12 stone is a special place. Very relaxing and wonderful people. Coffee and snacks provided. Everything was explained so I had no fear. I highly recommend this place.
Connie Gage
a month ago via Google
Twelve Stone made me feel welcome from the minute I walked in the door. I am usually a very hard stick but the nurse was wonderful and got the IV first try. They explained everything every step of the way!! If you need infusions this is the place to go
Jennifer Shipley
a month ago via Google
As usual the ladies at the Knoxville office went out of their way make me feel welcome and comfortable. Their professionalism and knowledge of what they were doing and the benefits I would receive from the medication being administered was comforting and reassuring. I especially want to give a shout-out to and for Lexi, Donna, and Kendra for their personal attention during my infusion. Thank you all again even if I didn't mention you by name I'm old and senile.
d w peterson
a month ago via Google
I went to the infusion center in Knoxville. My doctor prescribed iron infusions after several blood transfusions. I was VERY nervous doing this but TwelveStone was so wonderful. They make sure you are comfortable and have a very comfy friendly environment. Highly recommend.
Audrey White
6 months ago via Google
The entire staff at TwelveStone Infusion Center showed a very caring attitude. I've been to several infusion centers across the U.S. and TwelveStone is the most helpful, caring Center I've been to. It is also a very comfortable, warm facility. I recommend it VERY highly.
Ron Schmidt
6 months ago via Google
Everyone at the clinic made me feel safe, secure and comfortable. They were all very friendly and caring and they were constantly making sure I was okay. Thank you to everyone at TwelveStone for making my experience so wonderful.
Keith Smith
5 months ago via Google
We started a new journey on an Alzheimer’s treatment. Best Infusions Center we have ever been to. The caring ways, respect and grace of the Doctors and Nurses towards my mother in law, made us feel like family. It may seem like a long chapter in our lives, but with the Lord walking alone us, and the Twelve Stone Health Partners made the walk in the valley of fears much easier. They don’t just take care of their patients, but give them Hope for the best recovery in the Lord’s arms. Very loved.
Nirssa Dearinger
4 weeks ago via Google
My husband has been a patient at this facility for over a year and we HIGHLY recommend. Every member of the staff is professional and compassionate. The respect and kindness they show each other does not go unnoticed. We cannot imagine a better staff anywhere!! We love them. Extra bonus, private rooms, snacks and Netflix!
Wanda Long
4 months ago via Google
wonderful place. Rachel and Lexi were absolutely the nicest people and most professional that I have experienced. Infusions are not my favorite thing to do, but they make it easy and painless. Highly suggest anyone to go to this place and experience it for yourself.
Steven Brooks
3 months ago via Google
We meet all of your needs for infusion treatment and nutrition on your schedule.

More Information
TwelveStone Infusion Centers are contracted with the Insurance Plans listed below.
Please Note: This list may not be comprehensive and is subject to change without notice. To ensure that TwelveStone Infusion Centers are in-network please contact the customer service department on the back of the member identification card or contact us directly at 844-893-0012.
Aetna
Ambetter
Ascension Personalized Care
BCBS of Tennessee
Cigna
Cigna HealthSpring
Department of Veteran Affairs Health Plan
Devoted Health Plans
Farm Bureau Health Plans
Humana/ChoiceCare
Medicaid (TNCare)
Medicare and Railroad Medicare
Oscar Health Plan
Prime Health Services
Sonder Health Plan
TriCare East
United Healthcare/Oxford
WellCare
WellPoint
Medicare Advantage
Aetna
Blue Advantage (BCBS of TN)
Cigna HealthSpring
Devoted Health Plans
Farm Bureau Health Plans
Humana
Sonder Health Plan
United Healthcare
WellCare Health Plans
Managed Medicaid
BlueCare/TennCare Select (BCBS of TN)
United Healthcare Community Plan
WellPoint
Health Insurance Exchange/Marketplace
Ambetter
Ascension Personalized Care
BCBS of Tennessee
Cigna
Oscar Health Plan
United Healthcare
We believe in patient-centered care that helps you face your health conditions with strength and dignity. With more than 35 years of experience, our care coordinators follow you throughout your healthcare journey to ensure that everything is just right. We know you have enough to worry about, and our goal is to care for you in a safe, comfortable, Christian-oriented environment.
Your doctor has prescribed infusion treatments for your illness. If you’re a little nervous, that’s understandable. Navigating your first infusion can be intimidating, but everyone at 12Stone Infusion is here to make the first time a walk in the park!
For the sake of brevity, these tips apply whether you’re having your infusions administered at home or are coming to one of our comfortable centers. Your physician has likely discussed infusion therapy with you, but here are a few reminders.
Gather Your Information
Don’t wait until the last minute to find important documents. Assemble everything you’ll need and put it in a folder or notebook. That way, you won’t be scrambling to find forms before treatment. The documents you will need include,
- Insurance card and form of identification
- Medical history and list of other medications
- Forms required by the infusion center. It’s very likely that there will be forms on the infusion center website that you will need to complete before your appointment. (If you’re visiting us, you’ll find the forms online in the upper right corner in the green box. Complete the form(s) required by the type of infusion medication.) If there aren’t any, call and ask for them. Don’t wait until you’re at your appointment to complete them, especially if you’re a little nervous.
Arrange for Transportation
If you’re visiting a TwelveStone Infusion Center for the first time, we recommend arranging for transportation. Why? You may have side effects like weakness, sleepiness or feeling dizzy. Until you know for certain, have a way of getting home other than driving yourself. Many insurance plans cover the cost of a rideshare service (like Uber or Lyft). Check your plan.
Gather Your Comfort Items
12Stone will do whatever is possible to make you feel comfortable. We have reclining chairs, pillows, blankets, TV, and WiFi. We also provide beverages to keep you hydrated during your treatment. However, if a personal item, such as a stuffed animal, your bible, your favorite music or a crossword puzzle will help relax you, we completely understand, so bring it.
Day of Treatment
Your physician may have given you specific instructions to follow before your infusion, such as medications you may take, what to eat, or if special blood work is needed and has been ordered. Follow those instructions. And we cannot recommend this enough: Stay hydrated! Drinking ample non-caffeinated beverages will “plump” your veins, making that needle stick a little more pleasant. And of course, wear comfy clothing.
At Your Treatment
You’ll submit your paperwork, possible have some bloodwork done, and you’ll settle in for your treatment. At any time, feel free to ask questions. Our clinicians welcome your questions, so ask us anything! And if something doesn’t feel quite right, speak up. Communication will help ensure a smooth experience.
After Your Infusion
Your first infusion is complete! Before you go, make sure you’re feeling steady on your feet and ask any follow-up questions you may have. It’s likely your healthcare provider will follow-up with you after your first infusion.
The Next Time Now you know what to expect and can adjust your next visit accordingly. Perhaps you feel that you can drive home without a problem. Maybe bring your laptop and get a little work done. Or maybe you’d like to have a friend with you the next time. It doesn’t matter, we just want you to have the best experience possible every time you visit.
Ideally, wear something that makes you comfortable. If you like jeans, that’s great. Prefer sweatpants or leggings? Go for it. Anything that you would lounge around and at home is perfect. Our goal is that you feel as comfortable as possible while relaxing in a private suite.
TwelveStone is dedicated to meeting the needs of patients with complex and chronic conditions. We care for patients who’ve been diagnosed with multiple sclerosis, cystic fibrosis, leukemia, emphysema, psoriasis, osteoporosis, ulcerative colitis, rheumatoid arthritis, hypercholesterolemia, growth deficiency, and more.
We understand that being diagnosed with a chronic condition is a life-altering moment. That’s why we offer our Peer Advocates Support Services. We’ll connect you with real patients living with the same condition that can walk with you. Most importantly, we will pray with you and for you so that you never forget that God’s loving arms are here to hold you up when you are down.
If you’ve been hospitalized, you may have had an infusion already. Infusion is a process of administering medication. You’ll receive an IV needle, and medication will be put into an IV bag with saline to slowly drip into your bloodstream. Depending on several factors, the treatment can last less than an hour to several hours.